Neanderthal and Denisovan retroviruses in modern humans
نویسندگان
چکیده
منابع مشابه
Neanderthal and Denisovan retroviruses in modern humans
distribution of the surrounding downwelling light. Deep-sea fishes that have instead evolved to detect bioluminescent point sources have eyes constructed accordingly, typically having a high spatial resolution provided by a retinal area of tightly packed visual cells arranged in a deep pit-like fovea. Their eyes, though, are often quite small, with pupils only as large as necessary to detect po...
متن کاملNovel Denisovan and Neanderthal Retroviruses
Following the recent availability of high-coverage genomes for Denisovan and Neanderthal hominids, we conducted a screen for endogenized retroviruses, identifying six novel, previously unreported HERV-K(HML2) elements (HERV-K is human endogenous retrovirus K). These elements are absent from the human genome (hg38) and appear to be unique to archaic hominids. These findings provide further evide...
متن کاملNeandertal and Denisovan retroviruses
Further reading Baillie, J.K., Barnett, M.W., Upton, K.R., Gerhardt, D.J., Richmond, T.A., De Sapio, F., Brennan, P.M., Rizzu, P., Smith, S., Fell, M., et al. (2011). Somatic retrotransposition alters the genetic landscape of the human brain. Nature 479, 534–537. Beck, C.R., Garcia-Perez, J.L., Badge, R.M., and Moran, J.V. (2011). LINE-1 elements in structural variation and disease. Annu. Rev. ...
متن کاملThe Mitonuclear Dimension of Neanderthal and Denisovan Ancestry in Modern Human Genomes
Some human populations interbred with Neanderthals and Denisovans, resulting in substantial contributions to modern-human genomes. Therefore, it is now possible to use genomic data to investigate mechanisms that shaped historical gene flow between humans and our closest hominin relatives. More generally, in eukaryotes, mitonuclear interactions have been argued to play a disproportionate role in...
متن کاملThe Combined Landscape of Denisovan and Neanderthal Ancestry in Present-Day Humans
Some present-day humans derive up to ∼5% [1] of their ancestry from archaic Denisovans, an even larger proportion than the ∼2% from Neanderthals [2]. We developed methods that can disambiguate the locations of segments of Denisovan and Neanderthal ancestry in present-day humans and applied them to 257 high-coverage genomes from 120 diverse populations, among which were 20 individual Oceanians w...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2013
ISSN: 0960-9822
DOI: 10.1016/j.cub.2013.10.028